BARIUM LEVELS IN THE PROSTATE OF THE NORMAL HUMAN: A REVIEW

  • Vladimir Zaichick Radionuclide Diagnostics Department, Medical Radiological Research Centre, Obninsk, 249036, Russia.
10.22270/ujpr.v6i1.541

Keywords:

Barium, human prostate gland, normal prostatic tissue, biomarkers

Abstract

Knowledge of the etiology and pathogenesis of most prostate malfunctions and pathologies is very limited. Despite advances in medicine, the differential diagnosis of benign hypertrophic and carcinogenic prostate has steadily increased in complexity and controversy. It has been suggested that the prostate barium level (Ba) may help solve these problems related to prostate disorders, especially as an indicator of prostate cancer risk, as an elevated Ba level in the prostate may be a sign of prostate cancer in the future. These suggestions promoted more detailed studies of the Ba level in the prostate of healthy men. In present review we analyze data published concerning Ba prostatic levels in healthy persons.  In all 2194 items in the literature of the years dating back to 1921 were identified in the following databases: PubMed, Scopus, Web of Science, the Cochrane Library, ELSEVIER-EMBASE and Google.  This data was subject to an analysis employing both the “range” and “median” of means.  In this way the disparate nature of published Ba content of normal prostates was evaluated. Of the articles examined, 20 were selected for objective analysis of data from 1049 healthy subjects. The contents of prostatic Ba (on a wet mass basis) spanned the interval from 0.021 mg/kg to 222 mg/kg with 0.26 mg/kg as median for their means. The data included a wide range of values ​​and the samples were small, hence it is advisable that further studies with strong quality control of results be performed.

                   rw21.gif

Peer Review History:

Received 10 January 2021; Revised 2 February; Accepted 4 March, Available online 15 March 2021

Academic Editor: Prof. Dr. Gorkem Dulgerorcid22.jpg, Duzce University, Turkey, gorkemdulger@yandex.com

Received file:blue_23983.gif                Reviewer's Comments:download_logo_r_29189.gif

Average Peer review marks at initial stage: 6.5/10

Average Peer review marks at publication stage: 8.5/10

Reviewer(s) detail:

Dr. U. S. Mahadeva Raoorcid22.jpg, Universiti Sultan Zainal Abidin, Terengganu Malaysiaraousm@gmail.com

Prof. Dr. Hassan A.H. Al-Shamahyorcid22.jpg, Sana'a University, Yemen, shmahe@yemen.net.ye

Similar Articles:

LEVEL OF LEAD IN THE BLOOD AMONG FUEL STATION EMPLOYEES AND ITS RELATIONSHIP TO IMPAIRED LIVER AND KIDNEY FUNCTIONS IN DAMASCUS; SYRIA: OCCUPATIONAL EXPOSURE TO LEAD

 INTERLEUKIN-22 SERUM LEVELS IN PATIENTS WITH RHEUMATOID ARTHRITIS IN SANA'A CITY, YEMEN

 PLASMA FERRITIN AND HEPCIDIN LEVELS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

Downloads

Download data is not yet available.
Crossmark
Statistics
206 Views | 200 Downloads
Dimension Citations

Published

2021-03-03

How to Cite

Zaichick, V. “BARIUM LEVELS IN THE PROSTATE OF THE NORMAL HUMAN: A REVIEW”. Universal Journal of Pharmaceutical Research, vol. 6, no. 1, Mar. 2021, doi:10.22270/ujpr.v6i1.541.

Issue

Section

Review Articles