EFFECT OF DIETARY FACTORS AND NUTRITIONAL STATUS ON SERUM CALCIUM AND PHOSPHORUS LEVELS IN CKD PATIENTS ON TREATMENT IN A TERTIARY CARE SETTING IN NORTH INDIA

  • Babita Bansal Department of Physiology, Gian Sagar Medical College and Hospital, Ramnagar, Rajpura, Punjab, India.
  • Jaspreet Takkar Department of Physiology, Gian Sagar Medical College and Hospital, Ramnagar, Rajpura, Punjab, India.
  • Deepak Agrawal Department of Orthopaedics, Gian Sagar Medical College and Hospital, Ramnagar, Rajpura, Punjab, India.
  • Sushila Gahlot Department of Physiology, Gian Sagar Medical College and Hospital, Ramnagar, Rajpura, Punjab, India.

Abstract

Objective: The control of phosphorus and calcium metabolism is one of the objectives in treatment protocol for CKD patients. The levels of these minerals in serum are affected by dietary patterns and nutritional status of the patients. India being a large country, diet patterns vary from one state to another. Thus, we suspect a close association between dietary intake and alterations in homeostasis of calcium and phosphorus in CKD patients. Therefore, we conduct this study to describe the effect of dietary factors and nutritional status on serum calcium and phosphorus levels in CKD patients on treatment in a tertiary care setting in North India.


Methods: In the present study 330 CKD patients coming to dialysis unit, were recorded with detailed Medical history as well as baseline demographic data. Also, biochemical analysis of serum albumin corrected, calcium, phosphorus, and serum albumin of all cases were done using fully automated equipment. All statistical analyses were performed using SPSS statistical software.


Results: Majority (58.2 %) of the study patients were vegetarians with a mean value of BMI (Mean±SD=23.75±4.70 kg/m2). A negative but significant correlation was found between corrected calcium and phosphorus with 0.05 level of confidence interval (r=-0.149, p= 0.007).


Conclusion: It was found that the well-nourished patients were more likely to be hyperphosphatemic as compared to poorly nourished patients, but statistically the values were found to be nonsignificant (Statistically p-value was not less than 0.05).


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Peer Review History:


Received 23 November 2019;   Revised 12 December 2019; Accepted 1 January, Available online 15 January 2020


Academic Editor: Dr. Ali Abdullah Al-yahawiorcid22.jpg, Al-Razi university, Department of Pharmacy, Yemen, alyahawipharm@yahoo.com


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Received file:blue_23983.gif                Reviewer's Comments:download_logo_r_29189.gif


Average Peer review marks at initial stage: 6.5/10


Average Peer review marks at publication stage: 8.5/10


Reviewer(s) detail:


Dina Abd Elfattah Eldakhsorcid22.jpg, Pharos university (PUA), Egypt, dina_eldakhs@yahoo.com


Dr. Mohammad Tauseeforcid22.jpg, Department of Pharmaceutical Sciences, College of Pharmacy, Chicago State University, mtauseef@csu.edu


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Keywords: Calcium, CKD patients, diet, nutrition, phosphorus

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Bansal, B., J. Takkar, D. Agrawal, and S. Gahlot. “EFFECT OF DIETARY FACTORS AND NUTRITIONAL STATUS ON SERUM CALCIUM AND PHOSPHORUS LEVELS IN CKD PATIENTS ON TREATMENT IN A TERTIARY CARE SETTING IN NORTH INDIA”. Universal Journal of Pharmaceutical Research, Vol. 4, no. 6, Jan. 2020, doi:https://doi.org/10.22270/ujpr.v4i6.337.
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Research Articles