POTENTIAL OF SNAKEHEAD FISH (OPHIOCEPHALUS STRIATUS) IN ACCELERATING WOUND HEALING
Snakehead fish (Ophiocephalus striatus) (SF) is a type of fish that lives in fresh water and is widely known by the public. The properties and uses of SF have been scientifically proven to increase albumin levels and immune system as well as speed up the process of post-operative wound healing. The nutritional content of SF consists of albumin protein, amino acids, unsaturated fatty acids and minerals. Bioactive compounds that play a role in accelerating the wound healing process are albumin, glycine, and zinc (Zn). Wound healing is very dependent on the biochemical processes that occur on the skin involving intrinsic and extrinsic factors. This healing process will be accelerated with the help of dried SF extract which is designed in topical form such as cream or gel. Among albumin, glycine and Zn are important for wound healing because this protein is able to bind Zn and carry it in blood plasma. Zn deficiency reduces the wound healing process. Because of this nutrient, and other vitamins, it is present in SF extract so that it can trigger the formation of Endothelial Progenitor Cells (EPC) and accelerate wound healing. The presence of Zn in SF extract is likely to be a key factor playing a role in wound healing and also increases the appetite of children. Zn is an important mineral in the structure and function of cell membranes. Zn supplementation can limit membrane damage which is caused by free radicals during inflammation. Furthermore, Zn is also involved in the immune system, from the defense system by the skin to the regulation of genes in lymphocytes.
Peer Review History:
Received 15 September 2019; Revised 1 November; Accepted 6 November, Available online 15 November 2019
UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency.
Average Peer review marks at initial stage: 6.0/10
Average Peer review marks at publication stage: 7.5/10
Name: Asmaa Ahmed Mohamed Ahmed Khalifa
Affiliation: Pharos University, Alexandria, Egypt
Name: Dr. Marwa A. A. Fayed
Affiliation: University of Sadat City, Egypt
Comments of reviewer(s):